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Generic (Route) Brand Initial Dose (mg) Max Total Daily Dose (mg) Time to Max Concentration (min) Time Before Repeat Administration (min)
Oral
Risperidone (PO) Risperdal® 2 6 60 120
Olanzapine (PO) Zyprexa® 5 – 10 20 360 120
Haloperidol (PO)* Haldol® 5 20 30 – 60 15
Lorazepam (PO) Ativan® 2 12 20 – 30 120
Intramuscular
Lorazepam (IM) Ativan® 2 12 20 – 30 120
Ziprasidone (IM) Geodon® 10 40 15 120
Ziprasidone (IM) Geodon® 20 40 15 240
Olanzapine (IM) Zyprexa® 5 – 10 30 15 – 45 20
Aripiprazole (IM) Abilify® 9.75 30 60 120
Haloperidol (IM)* Haldol® 5 20 30 – 60 15
Intravenous
Haloperidol (IV)*† Haldol® 2 – 5 10 0 240
* Likely to cause higher incidence of extrapyramidal side effects than other recommended drugs
† Administering haloperidol intravenously increases risk of QT prolongation. Avoid if possible, especially in patients w/ borderline QT or taking other medication that can prolong QT. If given IV, limit dose and provide cardiac monitoring.

Dosing

Composite

+ Initial Dose

○ Max Total Daily Dose

Timing

Composite

+ Time to Max Concentration

○ Time Before Repeat Administration

References


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